Phosphorylation by MPK6: a conserved transcriptional modification mediates nitrate reductase activation and NO production?
作     者：Wang P, Du Y, Song CP.
刊物名称: Plant Signal Behav.
出版年份: 2011
卷: 6 ，期: 6，页码: 889-891
文章摘要 :  
Nitrate reductase is a central enzyme of nitrogen assimilation in plants. In a recent work, we have revealed MPK6 could phosphorylate Arabidopsis NIA2 at the serine 627 in hinge 2 region, this phosporylation may represent a rapid activation mechnism when plant need excessive nitrate reduction. Interestingly, all eukaryotic NRs have conserved docking sequence in their FAD domains, and many plant NR proteins have the conserved MAPK phosphorylation site. Those results indicated the MAPK cascades, the conserved signaling pathway also involved in lateral root development, mediated of NR phosporylation and NO generation. We noticed that the phosphorylation of S627 residue by MPK6 have a specially influence on the NO generation activity of NIA2. Although no homology of mammalian NOS has been identified in plants, NR may still share a similar regulation mechanism with mammalian NOS.