贾昆鹏,教授,硕士生导师
研究方向:棉花抗逆与遗传育种/类胡萝卜素代谢/苯丙烷类代谢
Email: kunpengjia_0515@126.com
通信地址:河南省开封市龙亭区 河南大学金明校区棉花生物学大楼326
个人简介
贾昆鹏,男,博士,现就职于河南大学棉花生物学国家重点实验室/生命科学学院。2019受聘河南大学杰出人才特区引进计划特聘教授第四层次。近年来在Science Advances、Molecular Plant、Nature Communications, PNAS, Plant Journal和Journal of Experimental Botany等高水平期刊发表论文20余篇,其中第一或通讯作者论文8篇。2019年以来先后主持两项国家自然科学基金和河南省优秀青年基金项目。
目前担任Plant Cell Reports杂志副主编。近年来受邀担任J Exp Botany、Front Plant Sci等植物学期刊的审稿人。
教育经历:
2004.9-2008.6 上海交通大学 植物科学与技术学士 导师:杨洪全教授
2008.9-2014.3上海交通大学 植物学博士 导师:杨洪全教授
工作经历:
2014.5-2017.5 阿卜杜拉国王科技大学 博士后 导师:Prof. Salim Al-Babili
2016.7-2016.9 杜克大学霍华德休斯研究中心 访问科学家 导师:Prof. Philip N. Benfey
2017.5-2019.10 阿卜杜拉国王科技大学 研究科学家 导师:Prof. Salim Al-Babili
讲授课程:
1.高级植物生理学;2.研究生文献阅读;3.研究生实践创新。
主要研究内容
利用遗传学,分子生物学及多组学研究植物类胡萝卜类激素(独角金内酯和脱落酸)和生物活性分子如何调控植物抗逆及生长发育。近几年主要研究成果包括:发现和鉴定了多个具有重要生物活性的类胡萝卜素代谢生物活性分子,包括anchorene, zaxinone;发现了植物体内一条脱落酸的非经典合成途径,为植物脱落酸合成途径研究做了重要补充;在独角金内酯与光信号转导互作以及独角金内酯类似物合成方面做出重要发现。未来主要聚焦于解析类胡萝卜素类与苯丙烷类代谢产物调控棉花生长发育与抗逆的分子机制研究,为培育优质、抗逆的棉花新品种做出贡献。
主持科研项目
1. 国家自然科学青年基金:与脱落酸互作的新颖脱辅基类胡萝卜素信号分子的筛选和鉴定(31900245),2020.1-2022.12,26万元
2. 国家自然科学基金面上项目:类胡萝卜素代谢活性分子anchorene调控拟南芥锚定根发育的分子机制(32170271),2022.1-2025.12,58万元
3. 河南省优秀青年基金:类胡萝卜素代谢与植物生长发育调控(222300420024),2022.1-2024.12,25万元
代表性论著(*通讯作者)
1. Alagoz, Y.; Mi, J.; Al-Babili, S.; Dickinson, A. J.; Jia, K. P. *, Screening for apocarotenoid plant growth regulators in Arabidopsis. In Methods in Enzymology, Academic Press: 2022, https://doi.org/10.1016/bs.mie.2022.03.067
2. Li, H., Zhang, S., Zhao, Y., Zhao, X., Xie, W., Guo, Y., Wang, Y., Li, K., Guo, J., Zhu, Q.-H., Zhang, X., Jia, K. P.*, Miao, Y. * Identification and Characterization of Cinnamyl Alcohol Dehydrogenase Encoding Genes Involved in Lignin Biosynthesis and Resistance to Verticillium dahliae in Upland Cotton (Gossypium hirsutum L.) Front Plant Sci 2022, doi: 10.3389/fpls.2022.840397
3. Zhang, S.; Guo, Y.; Zhang, Y.; Guo, J.; Li, K.; Fu, W.; Jia, Z.; Li, W.; Tran, L.-S. P.; Jia, K. P. *; Miao, Y. *, Genome-wide identification, characterization and expression profiles of the CCD gene family in Gossypium species. 3 Biotech 2021, 11, (5).
4. Jia, K. P.; Mi, J.; Ali, S.; Ohyanagi, H.; Moreno, J. C.; Ablazov, A.; Balakrishna, A.; Berqdar, L.; Fiore, A.; Diretto, G.; Martinez, C.; de Lera, A. R.; Gojobori, T.; Al-Babili, S., An alternative, zeaxanthin epoxidase-independent abscisic acid biosynthetic pathway in plants. Mol Plant 2021, 15 (1), 151-166
5. Jia, K. P.; Mi, J.; Ablazov, A.; Ali, S.; Yang, Y.; Balakrishna, A.; Berqdar, L.; Feng, Q.; Blilou, I.; Al-Babili, S., Iso-anchorene is an endogenous metabolite that inhibits primary root growth in Arabidopsis. Plant J 2021, 107 (1), 54-66
6. Ablazov, A.; Mi, J.; Jamil, M.; Jia, K. P.; Wang, J. Y.; Feng, Q.; Al-Babili, S., The Apocarotenoid Zaxinone Is a Positive Regulator of Strigolactone and Abscisic Acid Biosynthesis in Arabidopsis Roots. Front Plant Sci 2020, 11, 578.
7. Wang, J. Y.; Haider, I.; Jamil, M.; Fiorilli, V.; Saito, Y.; Mi, J.; Baz, L.; Kountche, B. A.; Jia, K. P.; Guo, X.; Balakrishna, A.; Ntui, V. O.; Reinke, B.; Volpe, V.; Gojobori, T.; Blilou, I.; Lanfranco, L.; Bonfante, P.; Al-Babili, S., The apocarotenoid metabolite zaxinone regulates growth and strigolactone biosynthesis in rice. Nat Commun 2019, 10, (1), 810.
8. Jia, K. P.; Dickinson, A. J.; Mi, J.; Cui, G.; Xiao, T. T.; Kharbatia, N. M.; Guo, X.; Sugiono, E.; Aranda, M.; Blilou, I.; Rueping, M.; Benfey, P. N.; Al-Babili, S., Anchorene is a carotenoid-derived regulatory metabolite required for anchor root formation in Arabidopsis. Sci Adv 2019, 5, (11), eaaw6787.
9. Jia, K. P.; Li, C.; Bouwmeester, H. J.; Al-Babili, S., Strigolactone Biosynthesis and Signal Transduction. In Strigolactones - Biology and Applications, Koltai, H.; Prandi, C., Eds. Springer International Publishing: Cham, 2019; pp 1-45.
10. Dickinson, A. J.; Lehner, K.; Mi, J.; Jia, K. P.; Mijar, M.; Dinneny, J.; Al-Babili, S.; Benfey, P. N., beta-Cyclocitral is a conserved root growth regulator. Proc Natl Acad Sci U S A 2019, 116, (21), 10563-10567.
11. Jia, K. P.; Baz, L.; Al-Babili, S., From carotenoids to strigolactones. J Exp Bot 2018, 69, (9), 2189-2204.
12. Baz, L.; Mori, N.; Mi, J.; Jamil, M.; Kountche, B. A.; Guo, X.; Balakrishna, A.; Jia, K. P.; Vermathen, M.; Akiyama, K.; Al-Babili, S., 3-Hydroxycarlactone, a Novel Product of the Strigolactone Biosynthesis Core Pathway. Mol Plant 2018, 11, (10), 1312-1314.
13. Samodelov, S. L.; Beyer, H. M.; Guo, X.; Augustin, M.; Jia, K. P.; Baz, L.; Ebenhoh, O.; Beyer, P.; Weber, W.; Al-Babili, S.; Zurbriggen, M. D., StrigoQuant: A genetically encoded biosensor for quantifying strigolactone activity and specificity. Sci Adv 2016, 2, (11), e1601266.
14. Jia, K. P.; Kountche, B. A.; Jamil, M.; Guo, X.; Ntui, V. O.; Rufenacht, A.; Rochange, S.; Al-Babili, S., Nitro-Phenlactone, a Carlactone Analog with Pleiotropic Strigolactone Activities. Mol Plant 2016, 9, (9), 1341-1344.
15. Luo, Q.; Lian, H. L.; He, S. B.; Li, L.; Jia, K. P.; Yang, H. Q., COP1 and phyB Physically Interact with PIL1 to Regulate Its Stability and Photomorphogenic Development in Arabidopsis. Plant Cell 2014, 26, (6), 2441-2456.
16. Jia, K. P.; Luo, Q.; He, S. B.; Lu, X. D.; Yang, H. Q., Strigolactone-regulated hypocotyl elongation is dependent on cryptochrome and phytochrome signaling pathways in Arabidopsis. Mol Plant 2014, 7, (3), 528-40.
专利
Al-Babili S. Jia, K. P., Dickinson A.J., (2019). Regulating Plant Growth Using a Diapocarotenoid. WO 2019/180638 A1