周树堂，博士，教授，博士生导师，河南大学棉花生物学国家重点实验室主任，中国科学院“百人计划”-引进国外杰出人才（A类），入选“国家百千万人才工程”，授予“国家有突出贡献中青年专家”，获“国务院政府特殊津贴”，“河南省优秀专家”,目前被聘为河南大学“杰出人才特区支持计划”特聘教授。2002年毕业于加拿大女皇大学(Queen’s University)，获生物化学与分子生物学博士学位。曾担任美国杜克大学助理教授，中国科学院动物研究所研究员，博士生导师，研究组长，河南农业大学生命科学院院长。从事农业昆虫与植物保护研究，系列研究成果揭示了昆虫大量繁殖、环境适应和暴发成灾的遗传基础，为害虫绿色防控提供了科技支撑。主持承担国家自然科学基金重点项目、NSFC-河南联合基金重点项目等10余项在PNAS、PLoS Genetics、Cellular and Molecular Life Sciences、Development、FASEB Journal、JBC、Insect Biochem Mol Biol等国际知名学术刊物发表研究论文20余篇，出版著作1部，申请发明专利3项。兼任国际昆虫激素顾问委员会委员，中国昆虫学会理事，发育与遗传专业委员会副主任，国际交流与合作工作委员会副主任，基因组专业委员会委员，Archives of Insect Biochemistry and Physiology、昆虫学报期刊等编委。
研究方向：
长期从事植物保护和昆虫学研究，运用基因组学、分子生物学、细胞生物学、遗传学等手段，解析昆虫生殖发育的内分泌调控机制、植物—昆虫—微生物互作以及害虫与天敌昆虫互作的分子机制。
研究工作经历：
2019-至今，河南大学棉花生物学国家重点实验室，主任，教授
2015-2019，河南大学生命科学学院，植物逆境生物学重点实验室，副主任，教授
2010–2015，中国科学院动物研究所，研究员，研究组组长
2005–2010，美国杜克大学(Duke University)，助理教授，助理研究员
2007–2009，河南农业大学生命科学院，院长（兼）
2003–2004，加拿大皇后大学，生物化学系与蛋白质功能中心，博士后
主要研究项目：
1. NSFC-河南联合基金重点项目，群居型飞蝗迁飞的分子调控机制（U1804232），直接经费209万元，2019.01-2022.12。
2. 国家基金委重点项目，飞蝗对环境变化生殖适应的内分泌调控机制研究（31630070），2017.01-2021.12，直接经费277万元。
3. 国家基金委面上项目，飞蝗卵子发生的microRNA调控机制研究（31372258），2014.01–2017.12，82万元。
4. 国家基金委面上项目，飞蝗性成熟期保幼激素作用的分子机制研究（31172149），2012.01-2015.12，61万元。
5. 国家“973” 项目子课题，害虫发育与变态的遗传机制（2012CB114101），2012.01－2016.12，100万元。
6. 中国科学院“百人计划”择优支持，2011.08- 2014.07，200万元。
7. 河南省高校科技创新团队支持计划，农业昆虫与害虫防治（16IRTSTHN011），2016.01-2017.12，100万元。
代表性论文（*通讯作者）：
1. Zheng H, Chen C, Liu C, Song Q. and Zhou S*. 2020. Rhythmic change of adipokinetic hormones diurnally regulates locust vitellogenesis and egg development. Insect Molecular Biology, 29: 283-292.
2. Song J, Zhou S*. 2019. Post‑transcriptional regulation of insect metamorphosis and oogenesis. Cellular and Molecular Life Sciences. doi: 10.1007/s00018-019-03361-5.
3. Guo W, Wu Z, Yang L, Cai Z, Zhao L, Zhou S*. 2019. Juvenile hormone-dependent Kazal-type serine protease inhibitor Greglin safeguards insect vitellogenesis and egg production. FASEB J. 33(1): 917-927.
4. Song J, Li W, Zhao H, Zhou S*. 2019. Clustered miR-2, miR-13a, miR-13b and miR-71 coordinately target Notch gene to regulate oogenesis of the migratory locust Locusta migratoria. Insect Biochem Mol Biol. doi: 106:39-46.
5. Song J, Li W, Zhao H, Gao L, Fan Y, Zhou S*. 2018. MicroRNA let-7 and miR-278 regulate insect metamorphosis and oogenesis via targeting juvenile hormone early response gene Krüppel-homolog 1. Development. 2145(24).
6. Jing YP, An H, Zhang S, Wang N, Zhou S*. 2018. Protein kinase C mediates juvenile hormone-dependent phosphorylation of Na+/K+-ATPase to induce ovarian follicular patency for yolk protein uptake. J Biol Chem. 293(52): 20112-20122.
7. Wu Z, Guo W, Yang L, He Q, Zhou S*. 2018. Juvenile hormone promotes locust fat body cell polyploidization and vitellogenesis by activating the transcription of Cdk6 and E2f1. Insect Biochem Mol Biol. 102: 1-10.
8. Luo M, Li D, Wang Z, Guo W, Kang L*, Zhou S*. 2017. Juvenile hormone differentially regulates two Grp78 genes encoding protein chaperones required for insect fat body cell homeostasis and vitellogenesis. J Biol Chem. 292(21): 8823-34.
9. Wang Z, Yang L, Song J, Kang L*, Zhou S*. 2017. An isoform of Taiman that contains a PRD-repeat motif is indispensable for transducing the vitellogenic juvenile hormone signal in Locusta migratoria. Insect Biochem Mol Biol. 82, 31-40.
10. Du M, Liu X, Ma N, Liu X, Wei J, Yin X, Zhou S, Ada R, Song Q, An S. 2017. Calcineurin-mediated dephosphorylation of Acetyl-coA Carboxylase is required for pheromone biosynthesis activating neuropeptide (PBAN)-induced sex pheromone Biosynthesis in Helicoverpa armigera. Mol Cell Proteomics. 16(12):2138-2152.
11. Wu Z, Guo W，Xie Y, Zhou S*. 2016. Juvenile hormone activates the transcription of Cell-division-cycle 6 (Cdc6) for polyploidy-dependent insect vitellogenesis and oogenesis. J Biol Chem. 291(10): 5418-27.
12. Guo W, Wu Z, Song J. Jiang F, Deng S, Walker VK, Zhou S*. 2014. Juvenile hormone-receptor complex acts on Mcm4 and Mcm7 to promote polyploidy and vitellogenesis in the migratory locust. PLoS Genetics. 10(10): e1004702.
13. Song J, Wu Z, Wang Z, Deng S, Zhou S*. 2014. Krüppel-homolog 1 mediates juvenile hormone action to promote vitellogenesis and oocyte maturation in the migratory locust. Insect Biochem Mol Biol. 52: 94-101.
14. Liu L, Zheng H, Jiang F, Guo W, Zhou S*. 2014. Comparative transcriptional analysis of asexual and sexual morphs reveals possible mechanisms in reproductive polyphenism of the cotton aphid. PLoS ONE. 9(6): e99506.
15. Ren D, Cai Z, Song J, Wu Z, Zhou S*. 2014. dsRNA uptake and persistence account for tissue-dependent susceptibility to RNA interference in the migratory locust,Locusta migratoria. Insect Mol Biol. 23(2): 175–184.
16. Song J, Guo W, Jiang F, Kang L, Zhou S*. 2013. Argonaute 1 is indispensable for juvenile hormone mediated oogenesis in the migratory locust, Locusta migratoria. Insect Biochem Mol Biol. 43(9): 879-887.
17. Zhou S*, Nissao E, Jackson IL, Leong W, Dancy L, Cuttitta F, Vujaskovic Z, Sunday ME*. Radiation-induced lung injury is mitigated by blockade of gastrin-releasing peptide. Am J Pathol. 2013. 182(4):1248-1254.
18. Zhou S, Degan S, Potts EN, Foster FM, Sunday ME. 2009. NPAS3 is a trachealess homolog critical for lung development and homeostasis. Proc Natl Acad Sci USA. 106(28), 11691-11696. Recommended by “Faculty of 1000”.
19. Levesque BM#, Zhou S#, Shan L, Kong Y, Sunday ME. 2007. NPAS1 regulates branching morphogenesis in embryonic lung. Am J Respir Cell Mol Biol. 36(4), 427-434. #Co-first authors.
20. Zhou S, Tejada M, Wyatt GR, Walker VK. 2006. A DNA-binding protein, tfp1, involved in juvenile hormone-regulated gene expression in Locusta migratoria. Insect Biochem Mol Biol. 36: 724-734.
21. Zhou S, Webb BA, Eves R, Mak AS. 2006. Effects of tyrosine phosphorylation of cortactin on podosome formation in A7r5 vascular smooth muscle cells. Am J Physiol Cell Physiol. 290, C463-471.
22. Webb BA, Zhou S, Eves R, Shen L, Jia L, Mak AS. 2006. Phosphorylation of cortactin by p21-activated kinase. Arch Biochem Biophys. 456, 183-193.
23. Eves R, Webb BA, Zhou S, Mak AS. 2006. Caldesmon is an integral component of podosomes in smooth muscle cells. J Cell Sci. 119, 1691-1702.
24. Webb BA, Eves R, Crawley SW, Zhou S, Côté GP, Mak AS. 2005. PAK1 induces podosome formation in A7r5 vascular smooth muscle cells in a PAK-interacting exchange factor-dependent manner. Am J Physiol Cell Physiol. 289: C898-907.
25. Hayward DC, Dhadialla TS, Zhou S, Kuiper MJ, Ball EE, Wyatt GR, Walker VK. 2003. Ligand specificity and developmental expression of RXR and ecdysone receptor in the migratory locust. J Insect Physiol. 49, 1135-1144.
26. Zhou S, Zhang J, Hirai M, Chinzei Y, Kayser H, Wyatt GR, Walker VK. 2002. A DNA-binding protein involved in gene regulation by juvenile hormone. Mol Cell Endocrinol. 190, 177-185.
27. Zhou S, Zhang J, Fam MD, Wyatt GR, Walker VK. 2002. Sequences of elongation factors-1a and -1g and stimulation by juvenile hormone in Locusta migratoria. Insect Biochem Mol Biol. 32, 1567-1576.
